The International Society for Stem Cell Research (ISSCR) has honored Stem Cell COREdinates and CorEUstem with the 2026 Public Service Award. These networks connect 79 core facilities, including Penn’s iPSC Core led by Dr. Wenli Yang, to facilitate collaboration and consistency. These programs foster a global connection that allows for shared expertise, new training opportunities, […]
Heavy menstrual bleeding is a common issue that affects millions of women, with a wide variety of causes from hormonal imbalances to conditions like fibroids to underlying issues like endometriosis. Unfortunately, it often goes overlooked and treatment options are limited. Dr. Kathleen O’Neill, Assitant Professor of Obstetrics and co-leader of the IRM Program on Reproductive […]
Recognized for his groundbreaking discovery of the DNA-sensing enzyme cyclic GMP-AMP synthase (cGas) and its role in immune and inflammatory response, the Institute for Regenerative Medicine at the University of Pennsylvania has awarded Zhijian ‘James’ Chen, PhD, the fifth Elaine Redding Brinster Prize in Science or Medicine. Dr. Chen’s discovery answers a fundamental question of how […]
Eoin Whelan, PhD and Ralph Brinster, VMD, PhD, along with a team of researchers at Penn’s School of Veterinary Medicine and Children’s Hospital of Philadelphia are featured in Penn Today for their recently published study in Stem Cell Reports. In the paper, they identify roadmap of how the complex development of male germ cell differentiation […]
A team of researchers led by Hongjun Song, PhD, and Guo-li Ming, MD, PhD (IRM Associate Director), are featured on the cover of the most recent issue of Cell Stem Cell! In this issue, Shen et al. reveal the critical role of N6-methyladenosine (m6A) RNA methylation in hypothalamic neurogenesis using both mouse models and a […]
Please join us in congratulating Dr. Dennis Discher on his election to the American Academy of Arts and Sciences! You can find the full announcement and list of new academy members here.
A team of researchers led by Hongjun Song, PhD, Guo-li Ming, MD, PhD (IRM Associate Director), and Dr. Donald O’Rourke, MD, used lab-grown organoids created from tumors of individuals with glioblastoma (GBM) to accurately model a patient’s response to CAR T cell therapy in real time. Their research, recently published in Cell Stem Cell, showed […]
Recognized for her discovery that variant forms of the BRCA1 gene impact hereditary breast cancer, the Institute for Regenerative Medicine at the University of Pennsylvania has awarded Mary-Claire King, PhD the fourth Elaine Redding Brinster Prize in Science or Medicine. Dr. King proved the existence and precise location of variants of the BRCA1 gene responsible […]
The IRM is happy to celebrate Yusha Sun of the Song Lab and Dr. Xin Wang of the Ming Lab for placing second in the 2024 BRAIN Initiative Photo and Video Contest for their image titled Chaos Circuitry. The image of rabies virus-mediated transsynaptic tracing reveals a vast landscape of neurons (orange) in the mouse […]
Dr. Bushra Raj, from the Perelman School of Medicine at the University of Pennsylvania, published an article in Nature Methods discussing how recent advancements in lineage tracing methods are enabling new insight into cell fate and trajectory during development. CRISPR–Cas9-based lineage analysis methods, imaging-based lineage analysis methods, and computational strategies are producing major impacts answering […]