A team of researchers led by IRM faculty member Kotaro Sasaki, PhD, MD, and Eoin Whelan, PhD recently published in Cell Stem Cell on their work to address male infertility.  In the paper, titled Generation of spermatogonia from human and non-human primate pluripotent stem cells, they report on a procedure that allows them to generate spermatogonia from both human and non-human primate pluripotent stem cells. The end goal is to produce mature, human sperm in the laboratory. There remain many challenges to achieving this outcome, but this work lays a foundation for studying the early stages of sperm development and causes of male infertility.

You can read the paper here.

Additionally, their work was featured in a Nature News piece!