Modeling human prenatal adrenocortical functional zonation dynamics from pluripotent stem cells
A team of researchers led by IRM faculty member Kotaro Sasaki, PhD, MD, and Michinori Mayama, PhD, MD, have recently been published in Cell Stem Cell for the development of an organoid system that models the complex tissue structure, development, and function in the developing human adrenal cortex. This work lays the foundation for research on regenerative therapies for adrenal diseases. You can read the full paper here.
This work has recently been featured in Penn Today. You can read the full press release here: Stress tested, testing stress: Novel organoid models how the adrenal gland develops
